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Panama & Colombia Deluxe: Panama City & Cartagena

7 Days
Prices From:
US$ 2,849

DELUXE | PRIVATE-GUIDED: Embark on this luxurious 7-day vacation across Panama and Colombia, pairing the gateway countries between Central and South America. Begin in dazzling and modern Panama City, where you'll explore the engineering marvel of the Panama Canal before exploring Panama City's historic centre on foot. Set off to discover Cartagena's Caribbean colonial charms, exploring historic landmarks during the day and enjoying the lively nightlife when the sun sets.

Begin your 7-day adventure with an immersive boat tour along the Panama Canal. Embark on a jungle expedition across Gatun Lake, passing by giant cargo ships contrasting against the verdant backdrop of natural tropical jungles. Keep your eyes peeled for incredible local wildlife, including three-toed sloths sleeping in tree branches, ospreys hunting for peacocks from the sky, communities of snail kites, and keel-billed toucans before searching for white-faced capuchins, mantled howler monkeys, and more wildlife on the lake's rainforest-clad islands.

Discover the rest of Panama City on foot with a half-day walking tour across the city's UNESCO-listed historic centre, Casco Antiguo. Step back into the 1600s as you stroll through the district’s colonial houses, narrow avenues, and historic churches, including the famous golden altar at the Church of San Jose. Visit the Plaza de Francia, paying tribute to the French contributions to the Panama Canal, Los Bovedas, a monument once used against pirate attacks, and some of the city’s best museums, including the Museo del Canal and the Museo de la Mola.

Fly to Colombia’s Caribbean coast and immerse yourself in the vibrant port city of Cartagena. Discover Cartagena’s most iconic sites, including the imposing San Felipe de Barajas Fortress, one of the city’s most distinctive landmarks atop the San Lazaro Hill, part of the city’s defence against pirates. Venture even higher to La Popa Convent, where you'll find a pristine gold-plated altar dedicated to the Virgin de la Candelaria, patron saint of the city. Discover the vendors and locals along the sun-kissed streets before the sun sets, and your discovery of Cartagena’s nightlife begins. Begin with a cocktail at a sea-view lounge and a delicious dinner at a local restaurant before embracing the salsa rhythms at a lively bar, creating an unforgettable and authentic Cartagena atmosphere.


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7 Days
Prices From:
US$ 2,849

Itinerary View Trip Map

Day 1

Welcome to Panama

Upon arrival to Panama City, please make your way through Customs and collect your baggage. Once you have made it to the Arrivals section of the airport, please look for a guide holding a sign with your name on it. This representative will take you to an awaiting vehicle and will transfer you to your hotel.

Accommodation: Hotel La Compañía

Duration3 Nights
Day 2

Panama Canal Wildlife Experience + VIP Visit to Miraflores Locks

Experience the Panama Canal and its lush surroundings from a unique perspective on a privately guided boat tour introducing you to the biodiverse ecosystem of this part of the Isthmus. After an early morning pick-up from your hotel lobby, along with your naturalist guide in tow, you will head to the town of Gamboa, where the Chagres River meets the Panama Canal. Here you will board a boat and start a jungle expedition across Gatun Lake in the Panama Canal. Pass by the giant cargo ships transiting the waterway and notice the sharp contrast they cast against the natural tropical surroundings. Along the way, watch out for the plethora of resident wildlife, including three toed sloths resting on tree branches, ospreys hunting for peacock basses, snail kites, keel-billed toucans, and many others. Your boat tour will circle several rainforest-clad islands on Gatun Lake in search for a variety of primates, such as the white-faced capuchin and mantled howler monkey. Your day continues as you visit Panama Canal’s Miraflores Locks where large ships transit the canal. Learn about the history of the Canal, marvel at the workings of this feat of human engineering and break for a tasty lunch. The tour then continues to the Panama Canal area, stopping by the town of Balboa, a former part of the Panama Canal Zone, and ends in the afternoon with a private transfer back to your hotel.

Meal Plan Breakfast and Lunch
Day 3

Casco Antiguo Walking Tour

During this half-day walking tour, which you can begin either in the morning or early afternoon, your private guide will take you to explore Panama City’s historic center, Casco Antiguo, which dates back to the late 1600's and has been declared a World Heritage Site by UNESCO. Step back in time as you walk through the district, surrounded by colonial houses, narrow avenues and impressive churches. Focusing on Panama’s early history, your guide will delve into the backstory of both the city and country as you explore its many sites of interest, such as The Flat Arch, the Cathedral, Las Bovedas and the French Plaza. After exploring historic Casca Antiguo, you will be returned to your hotel.

Meal Plan Breakfast
Day 4

Panama City to Cartagena

Following breakfast, transfer to the airport for your flight to Cartagena (flight not included in price).

Welcome to Colombia. After clearing customs and immigration formalities, meet your driver and transfer to the hotel.

This evening experience Cartagena's vibrant day-to-night transformation. Daytime brings lively streets filled with vendors and locals, while nights light up with a different energy. As the temperature cools, Cartageneros take to bars, restaurants, and plazas. Younger residents dance to salsa beats, while their elders enjoy fine dining. This tour offers a taste of Cartagena's nightlife, starting with a cocktail at a sea-view lounge like Café del Mar. Then, enjoy a delightful dinner at a local restaurant, each with its unique charm. The night ends at a local bar, perhaps Cafe Havana, where salsa rhythms and local dances create an unforgettable atmosphere. After a night out enjoying vibrant Cartagena, you will be returned to your hotel.

Accommodation: Ananda Boutique Hotel

Meal Plan Breakfast and Dinner
Duration3 Night
Day 5

San Felipe Colonial Fortress & La Popa Hilltop Convent

This half-day experience takes in two of the most iconic sights in Cartagena. Located just outside the historic old town, the imposing San Felipe de Barajas fortress is one of the city's most distinctive landmarks and is a formidable example of military might and architecture. Rising above the skyline, from this dominant vantage point the Spanish kept watch over the entrances to the city both by land and sea. San Felipe is the largest Spanish-built fortification in the New World, and along with the ramparts and stone walls was part of the city's defence against marauding pirates. Built on top of the San Lázaro hill, construction began in 1536 and continued for some 200 years. Underneath this amazing structure is a labyrinth of tunnels, many of which are still accessible. The sun-soaked fortifications are a living breathing history book, steeped with tales of old. The La Popa Convent sits in a privileged position, and is the highest landmark in the city. The convent started life as a humble and modest wooden chapel in the early 1600s but was later fortified and expanded to its current majesty. The cool, leafy, flower-filled courtyard and patio lead out to a viewing platform. From here there are panoramic vistas that stretch out over the city, old town, the bay of Cartagena, and the Caribbean Sea beyond. Inside the small chapel is the immaculate gold-plated and carved alter and ornate decoration dedicated to the "Virgin de la Candelaria", patron saint of the city. The convent still plays an important role in the life of the city's Catholics and is often full to bursting on religious holidays.

Meal Plan Breakfast
Day 6

Cartagena at Leisure

A full day to explore colonial Cartagena at your own pace.

Meal Plan Breakfast
Day 7

Depart Cartagena

Following breakfast, transfer to the Cartagena airport for your onward flight.

Meal Plan Breakfast

Other Information




  • Private arrival and departure airport transfers
  • 3 nights in deluxe accommodations in Panama City
  • 3 nights in deluxe accommodations in Cartagena
  • Private-guided Wildlife Experience with VIP Visit to Miraflores Locks
  • Private-guided Casco Antiguo Walking Tour
  • Private-guided "Cartagena by Night" tour
  • Private-guided walking tour of San Felipe & La Popa
  • Breakfast daily (excluding Day 1), 1 lunch, 1 dinner


  • Travel insurance
  • International and domestic airfare & airfare taxes
  • Meals and beverages not mentioned
  • Gratuities
  • Items of a personal nature
  • Visa fees if applicable


Prices are "from" per person based on twin/double share accommodation and for travel in low season. Seasonal surcharges and blackout dates may apply. Limited seat/spaces and all pricing is subject to change and availability. Rates for single or triple travellers are available on request - please inquire.

27 Aug 2024
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